Good to know: Visit and neighborhood recommendations in Winston-Salem This North Carolina gem offers a unique mix of Old Salem’s preserved colonial heritage and the bustling energy of innovation hubs and performing arts venues. Visitors can enjoy Southern cuisine, explore public art installations, or catch a play at the Hanesbrands Theatre. The city’s leafy parks, museums, and seasonal festivals create a welcoming atmosphere year-round. Winston-Salem is both a cultural retreat and a modern city on the rise. Top areas to stay at in Winston-Salem Downtown Winston-Salem Downtown Winston-Salem is a lively mix of historic buildings, modern skyscrapers, and a flourishing culinary and arts scene. Airbnbs here range from industrial lofts to cozy apartments within walking distance of restaurants, galleries, and nightlife. Staying downtown gives you immediate access to Innovation Quarter, Bailey Park, and live entertainment venues. Old Salem A beautifully preserved historic district, Old Salem offers a glimpse into 18th- and 19th-century Moravian life through living history exhibits and restored homes. Vacation rentals in the area often blend period charm with modern comfort, providing a unique and educational stay. The cobblestone streets and costumed interpreters make the neighborhood feel like a step back in time. Old Salem is ideal for history enthusiasts and families seeking a cultural immersion. Ardmore Located just southwest of downtown, Ardmore is a quiet, walkable neighborhood filled with early 20th-century homes and local charm. Airbnbs here are popular with visitors seeking a residential feel with easy access to Wake Forest Baptist Medical Center and downtown. The neighborhood features leafy streets, small parks, and welcoming coffee shops. Ardmore offers a peaceful and friendly atmosphere close to the city’s main attractions. Buena Vista Known for its tree-lined streets and upscale homes, Buena Vista is a picturesque neighborhood great for longer stays and family trips. Vacation rentals in this area often include spacious layouts, landscaped gardens, and elegant interiors. It's close to Reynolda House Museum of American Art and nearby boutique shopping and dining options. Buena Vista provides both comfort and proximity to cultural landmarks. West End Historic District The West End Historic District combines Victorian-era architecture with a growing number of cafes, craft breweries, and shops. Many vacation homes here are within walking distance of downtown yet offer a quieter and more artistic vibe. The neighborhood is known for its community feel and historic charm. West End is perfect for travelers looking for style, history, and creative energy. Must-visit places and attractions in Winston-Salem Old Salem Museums & Gardens At Old Salem Museums & Gardens, visitors can explore historic buildings, gardens, and exhibits that showcase Moravian traditions. The living history museum brings the 18th century to life with costumed interpreters and hands-on activities. Highlights include the Winkler Bakery and Single Brothers’ House. Reynolda House Museum of American Art Housed in a restored mansion, the Reynolda House Museum features an exceptional collection of American paintings, decorative arts, and historical exhibits. The estate includes formal gardens and walking trails open to the public. Visitors can learn about the Reynolds family, founders of R.J. Reynolds Tobacco Company. Kaleideum Downtown Formerly the Children’s Museum of Winston-Salem, Kaleideum Downtown offers interactive exhibits and creative play spaces for kids of all ages. It’s an engaging spot for families visiting the city, with programs that inspire learning through exploration. The museum encourages creativity, discovery, and fun. Kaleideum is perfect for a rainy-day activity or a break from historical tours. Bailey Park Located in the heart of the Innovation Quarter, Bailey Park is a popular outdoor space hosting food trucks, movie nights, yoga sessions, and community events. Surrounded by restored warehouses and startups, it reflects the city's forward-thinking spirit. It’s a great place to relax, mingle, or grab lunch between sightseeing. The park adds a modern twist to the Winston-Salem experience. Southeastern Center for Contemporary Art (SECCA) The Southeastern Center for Contemporary Art presents rotating exhibitions of cutting-edge visual art in a unique, modern space. SECCA hosts artist talks, performances, and educational workshops that explore timely themes. The museum is free to the public and located near scenic trails and neighborhoods. Hanesbrands Theatre A major performance venue in downtown, the Hanesbrands Theatre hosts live music, theater productions, film screenings, and special events. Its intimate setting allows for immersive cultural experiences in the heart of the city. The venue often features works from local artists as well as national touring acts. Reynolda Gardens Connected to the Reynolda House, Reynolda Gardens provides 125 acres of formal gardens, wooded trails, and greenhouses. Open year-round, it’s a peaceful oasis for walking, birdwatching, or enjoying seasonal blooms. The gardens are beautifully maintained and offer free public access. Bethabara Historic District Founded in 1753, the Bethabara Historic District preserves the site of the first Moravian settlement in North Carolina. Visitors can tour restored buildings, hike nature trails, and learn about early colonial life. Seasonal events and guided tours bring the history to life in engaging ways. Bethabara is a peaceful and educational place to connect with the region’s roots. Where to Find a Vacation Rental Near Winston-Salem, North Carolina Asheville, North Carolina Roughly two hours west, Asheville is a mountain town known for its vibrant arts scene, breweries, and historic architecture. Visitors can explore the Biltmore Estate, hike the Blue Ridge Parkway, and enjoy a wide range of dining options. Asheville adds a bold and creative complement to your Winston-Salem trip. Spend your stay in a vacation rental in Asheville with views of forested hills and access to artisan markets. Charlotte, North Carolina Located about 90 minutes south, Charlotte is North Carolina’s largest city and offers a fast-paced mix of culture, shopping, and professional sports. Visitors can explore the NASCAR Hall of Fame, Discovery Place, or enjoy nightlife in the South End. Charlotte is a modern urban contrast to Winston-Salem’s historic ambiance. Book a sleek apartment in Charlotte within walking distance of museums and city parks. Durham, North Carolina Just 80 minutes east, Durham is known for its revitalized downtown, tech industry, and thriving food scene. Attractions include the Durham Performing Arts Center, museums, and parks along the Eno River. Durham brings a youthful, energetic flair to a central North Carolina itinerary. Rest in a house in Durham near Duke University or tucked in a creative, walkable district. Boone, North Carolina Around two hours north, Boone is a charming mountain town home to Appalachian State University and stunning Blue Ridge views. Vacation homes here offer easy access to hiking, skiing, and scenic drives along the Blue Ridge Parkway. Boone combines outdoor adventure with college-town culture and seasonal festivals. Spend a cozy weekend in a cabin in Boone nestled among evergreens and mountain ridgelines. Greensboro, North Carolina Just 30 minutes east, Greensboro offers museums, a revitalized downtown, and strong ties to the Civil Rights Movement. Highlights include the International Civil Rights Center, Greensboro Science Center, and a lively brewery scene. Greensboro complements Winston-Salem with its historical weight and contemporary spirit. Stay in an airbnb in Greensboro close to Elm Street or near tranquil parkland. Explore dynamic urban landscapes and cultural treasures across diverse American cities. In Winston-Salem, the lively urban scene draws you into its unique blend of art-filled corridors and historical neighborhoods. When seeking vibrant city adventures, you may explore the rich industrial history and cultural sites by staying at rental accommodations in Rockford, where the Anderson Japanese Gardens offer a serene escape. For a touch of Californian sunshine mixed with charming urban vibes, consider rentals Redlands, where you can stroll through the Historic Downtown packed with boutique shops and galleries. Alternatively, the Southern charm of Fairhope airbnb options invites you to explore its fascinating coastal community and the scenic beauty of Mobile Bay. For those captivated by cultural heritage, delve into the array of local historical landmarks and then head to other iconic locations such as airbnb in Annapolis, where the charming cobblestone streets lead you to the United States Naval Academy and a variety of colonial-era structures. Enrich your cultural journey by opting for Appleton vacation rentals to explore the beautiful Hearthstone Historic House Museum. Lastly, the literary and artistic spirit is alive at Iowa City rental properties, a UNESCO City of Literature that offers a multitude of cultural festivals and events that will leave you inspired.